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  • Mazdutide (GLP-1/GCGR Dual Agonist) | 10mg x 10 Vials Kit | >99% Purity

Mazdutide (GLP-1/GCGR Dual Agonist) | 10mg x 10 Vials Kit | >99% Purity

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Chemical Specifications
Product Name Mazdutide (IBI362 / LY3305677)
CAS Number 2381031-15-0
Molecular Formula C214H335N55O71S
Molecular Weight ~4,836.4 g/mol (4.84 kDa)
Purity (HPLC) ≥ 99.0% (Clinical/Research Grade)
Target Receptors Dual Agonist (GLP-1R & GCGR)
Appearance White Lyophilized Powder
Storage Store at 2°C to 8°C (Protect from light and moisture)
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          Description
          🧬

          What is Mazdutide (IBI362)?

          Mazdutide (supplied in a massive 10mg x 10 Vials Kit) is universally recognized in research as “The Next-Gen Dual Power” of metabolic optimization. As a revolutionary mammalian oxyntomodulin (OXM) analogue, it acts as a highly potent GLP-1 and Glucagon (GCGR) Dual Receptor Agonist. While first-generation peptides induce passive weight loss purely by starvation, Mazdutide chemically forces the body into an active state of hyper-lipolysis. It actively elevates the Basal Metabolic Rate (BMR) and targets deep visceral fat clearance, making it the ultimate tool for overcoming severe metabolic resistance and shattering deep-rooted weight-loss plateaus.

          Key Features & Metabolic Breakthroughs

          ⚡

          Elevated Basal Metabolic Rate

          The Glucagon (GCGR) agonism completely overrides the body’s natural response to lower metabolism during caloric deficits. It chemically forces mitochondria to burn more energy at rest, turning the subject into an active furnace.

          🛡️

          Deep Visceral Fat Clearance

          Specifically targets the dangerous, stubborn ectopic fat surrounding internal organs (especially the liver). Clinical models show unparalleled speed in reversing fatty liver (NAFLD) and visceral adiposity.

          🚀

          Metabolic Plateau Breaker

          Designed for subjects who have built a profound tolerance to Semaglutide or Tirzepatide. By introducing the GCGR pathway, it forcefully re-ignites stalled weight loss through direct lipid oxidation.

          🍽️

          Supreme Satiety Control

          Simultaneously maintains a powerful grip on the GLP-1 receptor. It severely delays gastric emptying and silences neurological “food noise,” providing a massive caloric deficit without the sensation of starvation.

          🔥

          Active Lipolysis Synergy

          The synergy of dual agonism prevents the lean muscle wasting often seen in extreme diets. By directing the body to selectively oxidize fat stores for fuel, it supports profound shifts in overall body composition.

          🔬

          10mg High-Yield Clinical Format

          Delivered in an ultra-pure 10mg per vial format (100mg Total), providing researchers with the substantial dosing volume required for advanced, long-term dose-titration protocols.

          How It Works: Escaping “Passive Starvation” via the GCGR Engine

          The biggest failure in traditional obesity research is Metabolic Adaptation. When a subject uses a standalone GLP-1 agonist, they eat less. The body, sensing a sudden drop in calories, goes into “survival mode” and aggressively drops its Basal Metabolic Rate (BMR) to stop the weight loss. This is Passive Starvation—you are eating 1,200 calories, but your body is now only burning 1,100. The result is a total, unbreakable plateau.

          Mazdutide (IBI362) shatters this biological limitation via the Glucagon (GCGR) Engine. Oxyntomodulin naturally activates both the GLP-1 receptor (to stop you from eating) and the Glucagon receptor (to mobilize energy). Mazdutide perfectly mimics and amplifies this dual action.

          While the GLP-1 component successfully restricts caloric intake, the Glucagon component acts as an override switch for your metabolism. Instead of letting the BMR crash, Glucagon directly signals the liver and adipose tissue to undergo extreme lipolysis (fat breakdown) and thermogenesis (heat production). It forces the body to Actively Elevate Energy Expenditure. The result is an inescapable fat-burning environment: the subject is taking in very few calories (thanks to GLP-1) while simultaneously burning calories at an elevated, exercise-like rate at rest (thanks to GCGR). This specifically forces the rapid clearance of stubborn deep visceral and liver fat, allowing subjects to blow past plateaus that single-target therapies simply cannot breach.

          🧪 What’s In The Kit

          • Active Compound: Mazdutide (IBI362)
          • Classification: Dual GLP-1/GCGR Agonist
          • Format: 10-Vial Research Kit
          • Net Contents: 10mg per vial (100mg Total)
          • Purity: Clinical/Research Grade (≥99%)

          👩‍🔬 Who Uses It

          • Next-Gen Obesity & Metabolic Researchers
          • Hepatology Investigators (NAFLD/NASH)
          • Advanced Body Composition Specialists
          • Researchers Studying Metabolic Adaptation

          🔗 Best Paired With

          • Bacteriostatic Water (For sterile reconstitution)
          • Precision Insulin/Tuberculin Syringes
          • Refrigerated Storage (2°C – 8°C)
          • Continuous Glucose Monitoring (CGM)